NaturalProductMech

fischerindole L

naturalproductmech:mibig-be1bb908b0 MINTED SEEDED

Structure

Standard InChIKeyADPQVXWEVQETCB-UHFFFAOYSA-N
SMILES[C]=NC1C2c3c([nH]c4ccccc34)C(C)(C)C2CC(Cl)C1(C)C=C
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencescyanometdb:CyanoMetDB_1557, npatlas:NPA018655

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, other, from MIBiG.

Producer organisms 3

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Hapalosiphon welwitschii UTEX B 1830
NCBITaxon:1433842
SOURCE_ASSERTION mibig:BGC0000668 DOI:10.1016/s0040-4039(00)92061-6
Fischerella muscicola UTEX 1829
NCBITaxon:83542
SOURCE_ASSERTION mibig:BGC0001594 DOI:10.1016/j.bmc.2012.06.030
Fischerella sp. SAG 46.79
NCBITaxon:1930929
SOURCE_ASSERTION mibig:BGC0001595 PMID:28288107

Occurrences 0

None cited.

Biosynthetic gene clusters 3

AccessionHostLocus evidenceGenome
mibig:BGC0000668 Hapalosiphon welwitschii UTEX B 1830
NCBITaxon:1433842
CLUSTER_DEMONSTRATED genbank:KF811479.1
mibig:BGC0001594 Fischerella muscicola UTEX 1829
NCBITaxon:83542
CLUSTER_UNSTATED genbank:KY026487.1
mibig:BGC0001595 Fischerella sp. SAG 46.79
NCBITaxon:1930929
CLUSTER_UNSTATED genbank:KY026489.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000668, BGC0001594, BGC0001595. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0000668MIBIG5
BGC0001594MIBIG3
BGC0001595MIBIG3

This page is generated from data/natural_products/alkaloids/fischerindole-l.yaml, which is generated from the committed inventories. Neither is edited by hand.