NaturalProductMech

fumiquinazoline C

naturalproductmech:mibig-6fef67d3f2 MINTED SEEDED

Structure

Standard InChIKeyPOEYRUBMWIOMTB-QPPKQEJQSA-N
SMILES[H][C@]12N[C@@H](C)C(=O)N1C1=CC=CC=C1[C@@]21C[C@@]2([H])N3C(=O)C4=C(C=CC=C4)N=C3[C@](C)(NC2=O)O1
Stereochemistryfully defined
Cross-referencesnpatlas:NPA06491, pubchem:10003515

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Aspergillus fumigatus Af293
NCBITaxon:330879
BGC_CHARACTERIZED mibig:BGC0000355 PMID:21899262

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Aspergillus fumigatus
NCBITaxon:746128
LOTUS DOI:10.1007/S10600-005-0122-Y
Aspergillus fumigatus
NCBITaxon:746128
LOTUS DOI:10.1016/S0040-4039(00)91690-3

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000355 Aspergillus fumigatus Af293
NCBITaxon:330879
CLUSTER_DEMONSTRATED genbank:CM000174.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000355MIBIG5

This page is generated from data/natural_products/alkaloids/fumiquinazoline-c.yaml, which is generated from the committed inventories. Neither is edited by hand.