gladiofungin A
naturalproductmech:mibig-76bc5ac001 MINTED SEEDED
Structure
| Standard InChIKey | SYADJZZKJSIWKK-RAKBGESCSA-N |
|---|---|
| SMILES | CC1=C(C(=O)CCCCCCCC/C=C/[C@H](C)C(=O)C[C@H](O)CC2CC(=O)NC(=O)C2)C(=O)OC1O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA031554 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, nrps, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Burkholderia gladioli NCBITaxon:28095 |
BGC_CHARACTERIZED | mibig:BGC0002083 | DOI:10.1002/anie.202005711 |
| Burkholderia gladioli 238 NCBITaxon:28095 |
BGC_CHARACTERIZED | mibig:BGC0002087 | DOI:10.1002/anie.202005711 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Burkholderia gladioli NCBITaxon:28095 |
LOTUS | DOI:10.1002/ANIE.202005711 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002083 | Burkholderia gladioli NCBITaxon:28095 |
CLUSTER_DEMONSTRATED | genbank:WITE01000004.1 |
| mibig:BGC0002087 | Burkholderia gladioli 238 NCBITaxon:28095 |
CLUSTER_DEMONSTRATED | genbank:NZ_UZVS01000001.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0002083, BGC0002087. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002083 | MIBIG | 3 |
| BGC0002087 | MIBIG | 3 |
This page is generated from data/natural_products/alkaloids/gladiofungin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.