gonyautoxin 2

naturalproductmech:mibig-f1e9dbdade MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.

What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKey	ARSXTTJGWGCRRR-XXKOCQOQSA-N
SMILES	C1[C@H](C([C@@]23N1C(=N[C@H]([C@@H]2NC(=N3)N)COC(=O)N)N)(O)O)OS(=O)(=O)O
Stereochemistry	fully defined
Cross-references	pubchem:11593018, CHEBI:80769

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Cylindrospermopsis raciborskii T3 NCBITaxon:398006	SOURCE_ASSERTION	mibig:BGC0000188	PMID:18487408

Occurrences 7

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Saxidomus nuttalli NCBITaxon:1129274	LOTUS	DOI:10.1016/0041-0101(85)90159-X
Gonyaulax tamarensis NCBITaxon:2926	LOTUS	DOI:10.1021/JA00333A062
Gonyaulax tamarensis NCBITaxon:2926	LOTUS	DOI:10.1248/JHS1956.30.5_328
Gonyaulax tamarensis NCBITaxon:2926	LOTUS	DOI:10.1351/PAC198254101973
Mytilus californianus NCBITaxon:6549	LOTUS	DOI:10.1016/0041-0101(85)90159-X
Mizuhopecten yessoensis NCBITaxon:6573	LOTUS	DOI:10.1016/S0021-9673(01)88193-0
Cylindrospermopsis NCBITaxon:77021	LOTUS	DOI:10.1021/JA00433A072

Biosynthetic gene clusters 1

Accession	Host	Locus evidence	Genome
mibig:BGC0000188	Cylindrospermopsis raciborskii T3 NCBITaxon:398006	CLUSTER_UNSTATED	genbank:DQ787200.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

Explore across X-Mech

AntibioticMech (gonyautoxin 2) ↗ MediaIngredientMech (naturalproductmech:mibig-f1e9dbdade) ↗ TaxonMech: Cylindrospermopsis raciborskii T3 (NCBITaxon:398006) ↗ PathwayMech (mibig:BGC0000188) ↗

Provenance

Source concept	Source	Version
BGC0000188	MIBIG	5

This page is generated from data/natural_products/alkaloids/gonyautoxin-2.yaml, which is generated from the committed inventories. Neither is edited by hand.