grixazone A
CHEBI:73546 EXACT SEEDED
A cysteine derivative that is the S-(2-amino-8-formyl-3-oxo-3H-phenoxazin-1-yl) derivative of N-acetyl-L-cysteine.
Structure
| Standard InChIKey | CBXHEDPBKOZZSI-NSHDSACASA-N |
|---|---|
| SMILES | CC(=O)N[C@@H](CSC1=C(C(=O)C=C2C1=NC3=C(O2)C=CC(=C3)C=O)N)C(=O)O |
| Stereochemistry | fully defined |
| Cross-references | pubchem:71464599 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces griseus subsp. griseus NBRC 13350 NCBITaxon:455632 |
SOURCE_ASSERTION | mibig:BGC0000662 | DOI:10.7164/antibiotics.57.218 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1038/JA.2007.52 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.7164/ANTIBIOTICS.57.218 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000662 | Streptomyces griseus subsp. griseus NBRC 13350 NCBITaxon:455632 |
CLUSTER_UNSTATED | genbank:AP009493.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000662 | MIBIG | 5 |
| CHEBI:73546 | CHEBI | 3-star |
This page is generated from data/natural_products/alkaloids/grixazone-a.yaml, which is generated from the committed inventories. Neither is edited by hand.