guanitoxin
naturalproductmech:mibig-973a5e64e8 MINTED SEEDED
Structure
| Standard InChIKey | FYXHGVMFJYHPFX-ZCFIWIBFSA-N |
|---|---|
| SMILES | CN(C)C[C@H]1CN=C(N1OP(=O)(O)OC)N |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | cyanometdb:CyanoMetDB_0313, pubchem:114989 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Sphaerospermopsis torques-reginae ITEP-024 NCBITaxon:984208 |
BGC_CORRELATED | mibig:BGC0002148 | DOI:10.1021/jacs.2c01424 |
Occurrences 7
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Aphanizomenon flos-aquae NCBITaxon:1176 |
LOTUS | DOI:10.1016/0041-0101(86)90074-7 |
| Aphanizomenon flos-aquae NCBITaxon:1176 |
LOTUS | DOI:10.1016/S0040-4039(00)60994-2 |
| Aphanizomenon flos-aquae NCBITaxon:1176 |
LOTUS | DOI:10.1021/JA00202A057 |
| Aphanizomenon flos-aquae NCBITaxon:1176 |
LOTUS | DOI:10.1039/C39950000205 |
| Sphaerospermopsis oumiana NCBITaxon:747503 |
LOTUS | DOI:10.1016/J.HAL.2019.101737 |
| Sphaerospermopsis oumiana NCBITaxon:747503 |
LOTUS | DOI:10.1016/J.TOXICON.2009.07.017 |
| Anabaena oumiana NCBITaxon:747503 |
CYANOMETDB | PMID:19632258 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002148 | Sphaerospermopsis torques-reginae ITEP-024 NCBITaxon:984208 |
CLUSTER_DEMONSTRATED | genbank:CP080598.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002148 | MIBIG | 2 |
This page is generated from data/natural_products/alkaloids/guanitoxin.yaml, which is generated from the committed inventories. Neither is edited by hand.