NaturalProductMech

hydroxysporine

naturalproductmech:mibig-f2b2807434 MINTED SEEDED

Structure

Standard InChIKeyGIZMQINDJNQUDX-UHFFFAOYSA-N
SMILESOC1=CC2=C(C=C1)NC3=C2C(C(NC4)=O)=C4C5=C3NC6=CC=C(O)C=C65
Stereochemistryfully defined

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 0

None. The compound has a characterized gene cluster whose host NCBI does not name, which for an uncultured symbiont is the honest state — see the discussion below.

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001223 not named CLUSTER_UNSTATED genbank:KP274855.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

unnamed-producer — No producer claim is written from BGC0001223, which gives NCBITaxon:77133 (uncultured bacterium — shared by every unplaced bacterium), because the taxon names no single organism. The cluster is kept: a characterized locus is an origin assertion whether or not its host has a name, and for a compound from an uncultured symbiont that is the honest state. Name the producer if the primary literature does.

Provenance

Source conceptSourceVersion
BGC0001223MIBIG5

This page is generated from data/natural_products/alkaloids/hydroxysporine.yaml, which is generated from the committed inventories. Neither is edited by hand.