iodinin
naturalproductmech:mibig-97ae0794cf MINTED SEEDED cytotoxic
Structure
| Standard InChIKey | NBMOVCYIGUDQJE-UHFFFAOYSA-N |
|---|---|
| SMILES | C1=CC2=C(C(=C1)O)[N+](=C3C=CC=C(C3=[N+]2[O-])O)[O-] |
| Stereochemistry | fully defined |
| Cross-references | pubchem:135441735 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Xenorhabdus szentirmaii DSM 16338 NCBITaxon:1427518 |
BGC_CHARACTERIZED | mibig:BGC0001868 | PMID:30886436 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Nocardiopsis dassonvillei NCBITaxon:2014 |
LOTUS | DOI:10.1271/BBB1961.52.301 |
| Brevibacterium iodinum NCBITaxon:31943 |
LOTUS | DOI:10.1039/P19790002416 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001868 | Xenorhabdus szentirmaii DSM 16338 NCBITaxon:1427518 |
CLUSTER_DEMONSTRATED | genbank:NIBV01000002.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Bioactivities 9
| Assay | Result | Reference |
|---|---|---|
| NCI Yeast Anticancer Drug Screen. Data for the bub3 strain | ACTIVE | pubchem.aid:167 |
| NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain | ACTIVE | pubchem.aid:165 |
| NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain | ACTIVE | pubchem.aid:157 |
| NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain | ACTIVE | pubchem.aid:175 |
| NCI Yeast Anticancer Drug Screen. Data for the rad18 strain | ACTIVE | pubchem.aid:177 |
| NCI Yeast Anticancer Drug Screen. Data for the rad50 strain | ACTIVE | pubchem.aid:155 |
| NCI Yeast Anticancer Drug Screen. Data for the rad50EPP+ strain | ACTIVE | pubchem.aid:151 |
| NCI Yeast Anticancer Drug Screen. Data for the rad52 strain | ACTIVE | pubchem.aid:147 |
| NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain | ACTIVE | pubchem.aid:161 |
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001868 | MIBIG | 4 |
This page is generated from data/natural_products/alkaloids/iodinin.yaml, which is generated from the committed inventories. Neither is edited by hand.