NaturalProductMech

JBIR-126

naturalproductmech:mibig-6052c4ede5 MINTED SEEDED

Structure

Standard InChIKeyDNRWOARHBKGXQM-NMKZSIDYSA-N
SMILES[H][C@@]1(CCCN1)[C@H](NC(=O)[C@]1(C)COC(=N1)C1=CN(C)C2=CC(Cl)=CC(O)=C12)C(=O)NC(C)(CO)C(O)=O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA016046

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. NRRL F-4474
NCBITaxon:1463851
SOURCE_ASSERTION mibig:BGC0001368 PMID:27163034

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1016/J.TETLET.2015.07.080

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001368 Streptomyces sp. NRRL F-4474
NCBITaxon:1463851
CLUSTER_UNSTATED genbank:NZ_JOIB01000012.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001368MIBIG5

This page is generated from data/natural_products/alkaloids/jbir-126.yaml, which is generated from the committed inventories. Neither is edited by hand.