NaturalProductMech

leporin B

naturalproductmech:mibig-6752ae6cca MINTED SEEDED

Structure

Standard InChIKeyZAWHOLMDNIHGEJ-FPYGCLRLSA-N
SMILESCC(CCC1)C(C1C(/C=C/C)O2)C3=C2C(C4=CC=CC=C4)=CN(O)C3=O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Aspergillus flavus NRRL3357
NCBITaxon:332952
BGC_CHARACTERIZED mibig:BGC0001445 PMID:26051490

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Aspergillus flavus
NCBITaxon:5059
LOTUS DOI:10.1016/J.FGB.2015.05.010

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001445 Aspergillus flavus NRRL3357
NCBITaxon:332952
CLUSTER_DEMONSTRATED genbank:EQ963479.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001445MIBIG5

This page is generated from data/natural_products/alkaloids/leporin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.