NaturalProductMech

lynamicin A

naturalproductmech:mibig-3779efb61c MINTED SEEDED

Structure

Standard InChIKeyADBVWUJBUGOHJH-UHFFFAOYSA-N
SMILESCOC(=O)C1=C(C(=CN1)C1=CNC2=C1C=C(Cl)C=C2)C1=CNC2=C1C=C(Cl)C=C2
Stereochemistryfully defined
Cross-referencesnpatlas:NPA015907

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. SCSIO 03032
NCBITaxon:2878388
SOURCE_ASSERTION mibig:BGC0001782 PMID:28620687

Occurrences 4

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Actinomyces
NCBITaxon:1654
LOTUS DOI:10.1021/NP800286D
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1007/S12539-013-0200-Y
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1021/NP500362P
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1038/SREP42382

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001782 Streptomyces sp. SCSIO 03032
NCBITaxon:2878388
CLUSTER_UNSTATED genbank:KY750719.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001782MIBIG3

This page is generated from data/natural_products/alkaloids/lynamicin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.