NaturalProductMech

malbrancheamide A

naturalproductmech:mibig-1085be1f35 MINTED SEEDED

Structure

Standard InChIKeyDXPVAKSJZFQGSS-DQLDELGASA-N
SMILESCC1(C)[C@@H]2C[C@]34CCCN3C[C@@]2(CC2=C1NC1=CC(Cl)=CC=C21)NC4=O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA04108

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Malbranchea aurantiaca
NCBITaxon:78605
SOURCE_ASSERTION mibig:BGC0000816 PMID:23213353

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Malbranchea aurantiaca
NCBITaxon:78605
LOTUS DOI:10.1080/14786410802012361
Malbranchea aurantiaca
NCBITaxon:78605
LOTUS DOI:10.3109/14756366.2010.518964

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000816 Malbranchea aurantiaca
NCBITaxon:78605
CLUSTER_UNSTATED genbank:JQ708193.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000816MIBIG5

This page is generated from data/natural_products/alkaloids/malbrancheamide-a.yaml, which is generated from the committed inventories. Neither is edited by hand.