meleagrine
CHEBI:70399 EXACT SEEDED
An indole alkaloid with a heterotetracyclic skeleton isolated from Penicillium oxalicum.
Structure
| Standard InChIKey | JTJJJLSLKZFEPJ-WSHSOXHMSA-N |
|---|---|
| SMILES | CON1C2=C(C=CC=C2)[C@]2(C=C(O)C(=O)N3\C(=C\C4=CNC=N4)C(=O)N[C@]123)C(C)(C)C=C |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA010351 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Penicillium rubens Wisconsin 54-1255 NCBITaxon:500485 |
BGC_CHARACTERIZED | mibig:BGC0000420 | DOI:10.1371/journal.pone.0078922 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Penicillium NCBITaxon:5073 |
LOTUS | DOI:10.3923/PJBS.2014.667.674 |
| Penicillium oxalicum NCBITaxon:69781 |
LOTUS | DOI:10.1021/NP100470H |
| Penicillium oxalicum NCBITaxon:69781 |
CHEBI | PMID:21053938 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000420 | Penicillium rubens Wisconsin 54-1255 NCBITaxon:500485 |
CLUSTER_DEMONSTRATED | genbank:AM920436.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000420 | MIBIG | 5 |
| CHEBI:70399 | CHEBI | 3-star |
This page is generated from data/natural_products/alkaloids/meleagrine.yaml, which is generated from the committed inventories. Neither is edited by hand.