NaturalProductMech

migrastatin

naturalproductmech:mibig-4ea6daa815 MINTED SEEDED

Structure

Standard InChIKeyOGYMUMAKGYYNHV-DGAGQXFWSA-N
SMILESCOC1\C=C\CC\C=C\C(=O)OC(C(C)C(=O)CCCC2CC(=O)NC(=O)C2)\C(C)=C/C(C)C1O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA06168, pubchem:11016431

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces platensis subsp. rosaceus
NCBITaxon:684832
BGC_CHARACTERIZED mibig:BGC0000177 PMID:19726666

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000177 Streptomyces platensis subsp. rosaceus
NCBITaxon:684832
CLUSTER_DEMONSTRATED genbank:GQ274953.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000177MIBIG5

This page is generated from data/natural_products/alkaloids/migrastatin.yaml, which is generated from the committed inventories. Neither is edited by hand.