nematophin
naturalproductmech:mibig-ed3a69b3bc MINTED SEEDED
Structure
| Standard InChIKey | NIQUZFQMNMNAMD-UHFFFAOYSA-N |
|---|---|
| SMILES | CCC(C)C(=O)C(=O)NCCC1=CNC2=CC=CC=C12 |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA07705 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Xenorhabdus budapestensis NCBITaxon:290110 |
SOURCE_ASSERTION | mibig:BGC0001434 | DOI:10.1021/acs.orglett.6b03796 |
| Xenorhabdus nematophila ATCC 19061 NCBITaxon:406817 |
SOURCE_ASSERTION | mibig:BGC0001692 | PMID:28134534 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Xenorhabdus nematophila NCBITaxon:628 |
LOTUS | DOI:10.1139/M97-110 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001434 | Xenorhabdus budapestensis NCBITaxon:290110 |
CLUSTER_UNSTATED | genbank:KR871223.1 |
| mibig:BGC0001692 | Xenorhabdus nematophila ATCC 19061 NCBITaxon:406817 |
CLUSTER_UNSTATED | genbank:NC_014228.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0001434, BGC0001692. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001434 | MIBIG | 3 |
| BGC0001692 | MIBIG | 5 |
This page is generated from data/natural_products/alkaloids/nematophin.yaml, which is generated from the committed inventories. Neither is edited by hand.