NaturalProductMech

NG-391

naturalproductmech:mibig-27ad7f4a05 MINTED SEEDED

Structure

Standard InChIKeyOHWILISHWFHITP-OCKBFZBYSA-N
SMILESC/C=C(\C=C(/C)\C=C\C=C\C=C(/C)\C(=O)[C@@]12[C@@H](O1)[C@](NC2=O)(CCO)O)/C(=O)OC
Stereochemistryfully defined
Cross-referencesnpatlas:NPA004762, npatlas:NPA04762

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, nrps, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Fusarium sp.
NCBITaxon:29916
BGC_CHARACTERIZED mibig:BGC0002525 PMID:32139880
Metarhizium anisopliae
NCBITaxon:5530
SOURCE_ASSERTION mibig:BGC0001026 DOI:10.1021/jf061405r

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Fusarium
NCBITaxon:5506
LOTUS DOI:10.7164/ANTIBIOTICS.54.850
Metarhizium anisopliae
NCBITaxon:5530
LOTUS DOI:10.1021/JF061405R

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0002525 Fusarium sp.
NCBITaxon:29916
CLUSTER_DEMONSTRATED genbank:LC516401.1
mibig:BGC0001026 Metarhizium anisopliae
NCBITaxon:5530
CLUSTER_UNSTATED genbank:GQ176852.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0001026, BGC0002525. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0002525MIBIG3
BGC0001026MIBIG3

This page is generated from data/natural_products/alkaloids/ng-391.yaml, which is generated from the committed inventories. Neither is edited by hand.