Nocuolin A
naturalproductmech:mibig-b2e8c6c655 MINTED SEEDED
Structure
| Standard InChIKey | MPGIDXBHXRMMSY-UHFFFAOYSA-N |
|---|---|
| SMILES | CCCCCC1=NN(C(=O)CCO)OC(CCCCC)C1 |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA027423 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Nostoc sp. CCAP 1453/38 NCBITaxon:1570104 |
SOURCE_ASSERTION | mibig:BGC0001703 | DOI:10.1371/journal.pone.0172850 |
| Nodularia sp. HBU26 NCBITaxon:1966654 |
SOURCE_ASSERTION | mibig:BGC0001704 | PMID:28253280 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Nostoc NCBITaxon:1177 |
LOTUS | DOI:10.1371/JOURNAL.PONE.0172850 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001703 | Nostoc sp. CCAP 1453/38 NCBITaxon:1570104 |
CLUSTER_UNSTATED | genbank:KP143720.1 |
| mibig:BGC0001704 | Nodularia sp. HBU26 NCBITaxon:1966654 |
CLUSTER_UNSTATED | genbank:KY594676.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0001703, BGC0001704. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001703 | MIBIG | 3 |
| BGC0001704 | MIBIG | 3 |
This page is generated from data/natural_products/alkaloids/nocuolin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.