NaturalProductMech

pendolmycin

naturalproductmech:mibig-707112a6f4 MINTED SEEDED

Structure

Standard InChIKeyJPJWIAYMFHOJRY-YWZLYKJASA-N
SMILESCC(C)[C@H]1C(=O)N[C@@H](CC2=CNC3=C(C=CC(=C23)N1C)C(C)(C)C=C)CO
Stereochemistryfully defined

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Marinactinospora thermotolerans
NCBITaxon:531310
BGC_CHARACTERIZED mibig:BGC0000391 PMID:22362652

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Nocardiopsis
NCBITaxon:2013
LOTUS DOI:10.1021/NP50060A022
Nocardiopsis
NCBITaxon:2013
LOTUS DOI:10.1021/NP50077A040
Marinactinospora thermotolerans
NCBITaxon:531310
LOTUS DOI:10.1021/NP200399T

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000391 Marinactinospora thermotolerans
NCBITaxon:531310
CLUSTER_DEMONSTRATED genbank:JN634585.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000391MIBIG5

This page is generated from data/natural_products/alkaloids/pendolmycin.yaml, which is generated from the committed inventories. Neither is edited by hand.