NaturalProductMech

prodigiosin

CHEBI:82758 EXACT SEEDED antimicrobial unspecified

A member of the class of tripyrroles that is a red-coloured pigment with antibiotic properties produced by Serratia marcescens.

Structure

Standard InChIKeySZXDNGVQRDTJSD-VBKFSLOCSA-N
SMILESCCCCCC1=C\C(=C\C2=C(OC)C=C(N2)C2=CC=CN2)N=C1C
Stereochemistryfully defined

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Pseudoalteromonas rubra
NCBITaxon:43658
BGC_CHARACTERIZED mibig:BGC0002675 DOI:10.1128/spectrum.01171-21

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Escherichia coli
NCBITaxon:562
LOTUS DOI:10.1039/C8GC03728K
Serratia marcescens
NCBITaxon:615
LOTUS DOI:10.1038/SJ.BJP.0703614
Serratia marcescens
NCBITaxon:615
LOTUS DOI:10.1111/J.1365-2958.2005.04602.X
Serratia marcescens
NCBITaxon:615
CHEBI PMID:15853884
Vibrio gazogenes
NCBITaxon:687
LOTUS DOI:10.7164/ANTIBIOTICS.47.257

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002675 Pseudoalteromonas rubra
NCBITaxon:43658
CLUSTER_DEMONSTRATED genbank:CP045429.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Elsewhere in the fleet

Provenance

Source conceptSourceVersion
BGC0002675MIBIG2
CHEBI:82758CHEBI3-star

This page is generated from data/natural_products/alkaloids/prodigiosin.yaml, which is generated from the committed inventories. Neither is edited by hand.