prodigiosin

CHEBI:82758 EXACT SEEDED antimicrobial unspecified

What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

A member of the class of tripyrroles that is a red-coloured pigment with antibiotic properties produced by Serratia marcescens.

Structure

Standard InChIKey	SZXDNGVQRDTJSD-VBKFSLOCSA-N
SMILES	CCCCCC1=C\C(=C\C2=C(OC)C=C(N2)C2=CC=CN2)N=C1C
Stereochemistry	fully defined

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Pseudoalteromonas rubra Strain: S4059 NCBITaxon:43658	BGC_CHARACTERIZED	mibig:BGC0002675	DOI:10.1128/spectrum.01171-21 reference DOI:10.1128/spectrum.01171-21 evidence type DATABASE_ASSERTION notes MIBiG BGC0002675 entry version 2; citation taken from the compound evidence level reference DOI:10.1128/spectrum.01171-21 evidence type CURATOR_INFERENCE notes Strain context: S4059. Wang et al. test pigC deletion in P. rubra S4059 and identify its genome as CP045429. The published experiment is strain-specific. Taxon identity and evidence grade are unchanged; this is not a species-wide experiment. MIBiG source row BGC0002675:1; SHA256 d3b55b2c6b091c7c8da99f5634fdb02e208328c4dc1c317750a341bdef639de0. Curator: codex; date: 2026-10-13.

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Escherichia coli NCBITaxon:562	LOTUS	DOI:10.1039/C8GC03728K
Serratia marcescens NCBITaxon:615	LOTUS	DOI:10.1038/SJ.BJP.0703614
Serratia marcescens NCBITaxon:615	LOTUS	DOI:10.1111/J.1365-2958.2005.04602.X
Serratia marcescens NCBITaxon:615	CHEBI	PMID:15853884
Vibrio gazogenes NCBITaxon:687	LOTUS	DOI:10.7164/ANTIBIOTICS.47.257

Biosynthetic gene clusters 1

Accession	Host	Locus evidence	Genome
mibig:BGC0002675	Pseudoalteromonas rubra NCBITaxon:43658	CLUSTER_DEMONSTRATED	genbank:CP045429.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

Elsewhere in the fleet

AntibioticMech — CHEBI:82758 (same structure, same inchikey)

Explore across X-Mech

AntibioticMech (prodigiosin) ↗ MediaIngredientMech (CHEBI:82758) ↗ TaxonMech: Pseudoalteromonas rubra (NCBITaxon:43658) ↗ PathwayMech (mibig:BGC0002675) ↗

Provenance

Source concept	Source	Version
BGC0002675	MIBIG	2
CHEBI:82758	CHEBI	3-star

This page is generated from data/natural_products/alkaloids/prodigiosin.yaml, which is generated from the committed inventories. Neither is edited by hand.