NaturalProductMech

pyrichalasin H

naturalproductmech:mibig-65e7e765dd MINTED SEEDED

Structure

Standard InChIKeyAECZOENDDUTONS-PWSPGYJUSA-N
SMILESCC1C/C=C/C2C(C(=C)C(C3C2(C(/C=C/C(C1)(C)O)OC(=O)C)C(=O)NC3CC4=CC=C(C=C4)OC)C)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:6442793

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Pyricularia grisea
NCBITaxon:148305
BGC_CHARACTERIZED mibig:BGC0001881 PMID:31099577

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001881 Pyricularia grisea
NCBITaxon:148305
CLUSTER_DEMONSTRATED genbank:MK801691.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001881MIBIG4

This page is generated from data/natural_products/alkaloids/pyrichalasin-h.yaml, which is generated from the committed inventories. Neither is edited by hand.