pyrrolomycin B
naturalproductmech:mibig-041f0f3d58 MINTED SEEDED antibacterial
Structure
| Standard InChIKey | ZIOBWQJYKHDNKP-UHFFFAOYSA-N |
|---|---|
| SMILES | C1=C(C=C(C(=C1Cl)O)CC2=C(C(=C(N2)Cl)Cl)[N+](=O)[O-])Cl |
| Stereochemistry | fully defined |
| Cross-references | pubchem:133274 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces vitaminophilus NCBITaxon:76728 |
SOURCE_ASSERTION | mibig:BGC0000130 | PMID:17158935 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.7164/ANTIBIOTICS.34.1363 |
| Streptomyces vitaminophilus NCBITaxon:76728 |
LOTUS | DOI:10.1128/GENOMEA.01582-15 |
| Streptomyces vitaminophilus NCBITaxon:76728 |
LOTUS | DOI:10.7164/ANTIBIOTICS.36.1263 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000130 | Streptomyces vitaminophilus NCBITaxon:76728 |
CLUSTER_UNSTATED | genbank:EF140901.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — antibioticmech:aro-dfad12d850 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000130 | MIBIG | 5 |
This page is generated from data/natural_products/alkaloids/pyrrolomycin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.