pyrrolomycin C
naturalproductmech:mibig-d67af7736c MINTED SEEDED antibacterial
Structure
| Standard InChIKey | WEZZHODHNYWVJY-UHFFFAOYSA-N |
|---|---|
| SMILES | OC1=C(C=C(Cl)C=C1Cl)C(=O)C1=CC(Cl)=C(Cl)N1 |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA09712 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces vitaminophilus NCBITaxon:76728 |
SOURCE_ASSERTION | mibig:BGC0000130 | PMID:17158935 |
Occurrences 6
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.7164/ANTIBIOTICS.40.233 |
| Streptomyces fumanus NCBITaxon:67302 |
LOTUS | DOI:10.1002/CHIN.200543220 |
| Streptomyces fumanus NCBITaxon:67302 |
LOTUS | DOI:10.1021/NP0503404 |
| Streptomyces vitaminophilus NCBITaxon:76728 |
LOTUS | DOI:10.1128/GENOMEA.01582-15 |
| Streptomyces vitaminophilus NCBITaxon:76728 |
LOTUS | DOI:10.7164/ANTIBIOTICS.36.1263 |
| Streptomyces vitaminophilus NCBITaxon:76728 |
LOTUS | DOI:10.7164/ANTIBIOTICS.36.1483 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000130 | Streptomyces vitaminophilus NCBITaxon:76728 |
CLUSTER_UNSTATED | genbank:EF140901.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — antibioticmech:aro-c8e528eadd (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000130 | MIBIG | 5 |
This page is generated from data/natural_products/alkaloids/pyrrolomycin-c.yaml, which is generated from the committed inventories. Neither is edited by hand.