NaturalProductMech

pyrronazol B

naturalproductmech:mibig-ed84a7d9e1 MINTED SEEDED

Structure

Standard InChIKeyHVDWUEDXQDMWCX-CPGSKVSJSA-N
SMILESCOC1=CC(=O)O[C@H]([C@H]1C)C1=COC(=N1)C(\C)=C\C1=CC=C(Cl)N1
Stereochemistryfully defined
Cross-referencesnpatlas:NPA013257

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Nannocystis pusilla
NCBITaxon:889268
SOURCE_ASSERTION mibig:BGC0001750 PMID:28944573

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Nannocystis pusilla
NCBITaxon:889268
LOTUS DOI:10.1002/CHEM.201703782
Nannocystis pusilla
NCBITaxon:889268
LOTUS DOI:10.1021/NP400877R

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001750 Nannocystis pusilla
NCBITaxon:889268
CLUSTER_UNSTATED genbank:MF817819.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001750MIBIG4

This page is generated from data/natural_products/alkaloids/pyrronazol-b.yaml, which is generated from the committed inventories. Neither is edited by hand.