rebeccamycin
CHEBI:135511 EXACT SEEDED
An N-glycosyl compound consisting of a heteropolycyclic ring system with a glucosyl group attached to one of the indolic nitrogens.
Structure
| Standard InChIKey | QEHOIJJIZXRMAN-QZQSLCQPSA-N |
|---|---|
| SMILES | CO[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O)N2C3=C(C=CC=C3Cl)C4=C5C(=C6C7=C(C(=CC=C7)Cl)NC6=C42)C(=O)NC5=O)CO |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA08169, pubchem:73110 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Lechevalieria aerocolonigenes NCBITaxon:68170 |
SOURCE_ASSERTION | mibig:BGC0000821 | PMID:15743957 |
Occurrences 6
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Nocardia NCBITaxon:1817 |
LOTUS | DOI:10.1016/S0040-4039(00)89280-1 |
| Streptomyces lividans NCBITaxon:1916 |
LOTUS | DOI:10.1038/JA.2015.31 |
| Streptomyces sanyensis NCBITaxon:568869 |
LOTUS | DOI:10.3390/MD17100588 |
| Lechevalieria aerocolonigenes NCBITaxon:68170 |
LOTUS | DOI:10.1021/NP50059A020 |
| Lechevalieria aerocolonigenes NCBITaxon:68170 |
LOTUS | DOI:10.1128/JB.187.6.2084-2092.2005 |
| Lechevalieria aerocolonigenes NCBITaxon:68170 |
LOTUS | DOI:10.7164/ANTIBIOTICS.40.668 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000821 | Lechevalieria aerocolonigenes NCBITaxon:68170 |
CLUSTER_DEMONSTRATED | genbank:AB090952.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000821 | MIBIG | 5 |
| CHEBI:135511 | CHEBI | 3-star |
This page is generated from data/natural_products/alkaloids/rebeccamycin.yaml, which is generated from the committed inventories. Neither is edited by hand.