rotihibin A
naturalproductmech:mibig-0037b4bc65 MINTED SEEDED
Structure
| Standard InChIKey | ZLBAXRLUOZVNFP-ZLYGYSDWSA-N |
|---|---|
| SMILES | CCCCCCC/C=C/C(=O)N[C@H](CCCNC(=O)N)C(=O)N[C@H](CO)C(=O)N[C@H](CCNC(=O)[C@@H]([C@H](C)O)N)C(=O)N[C@H]([C@@H](C(=O)N)O)C(=O)N[C@H](CC(=O)N)CO |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA021263 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces scabiei 87.22 NCBITaxon:680198 |
BGC_CHARACTERIZED | mibig:BGC0002367 | PMID:34346752 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces halstedii NCBITaxon:1944 |
LOTUS | DOI:10.7164/ANTIBIOTICS.48.1004 |
| Streptomyces graminofaciens NCBITaxon:68212 |
LOTUS | DOI:10.7164/ANTIBIOTICS.48.1004 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002367 | Streptomyces scabiei 87.22 NCBITaxon:680198 |
CLUSTER_DEMONSTRATED | genbank:FN554889.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002367 | MIBIG | 2 |
This page is generated from data/natural_products/alkaloids/rotihibin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.