NaturalProductMech

safracin A

naturalproductmech:mibig-8828c74fc7 MINTED SEEDED

Structure

Standard InChIKeyAZDDAJXLYMVMAW-BVFBRMCBSA-N
SMILESCC1=C(C(=C2[C@H]3[C@@H]4CC5=C([C@@H](N4C[C@H](N3C)CC2=C1)CNC(=O)[C@H](C)N)C(=O)C(=C(C5=O)C)OC)O)OC
Stereochemistryfully defined
Cross-referencespubchem:160293

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Pseudomonas fluorescens
NCBITaxon:294
SOURCE_ASSERTION mibig:BGC0000421 PMID:15773985

Occurrences 4

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Pseudomonas fluorescens
NCBITaxon:294
LOTUS DOI:10.1111/J.1365-2958.2004.04433.X
Pseudomonas fluorescens
NCBITaxon:294
LOTUS DOI:10.7164/ANTIBIOTICS.36.1279
Pseudomonas fluorescens
NCBITaxon:294
LOTUS DOI:10.7164/ANTIBIOTICS.36.1284
Pseudomonas fluorescens
NCBITaxon:294
LOTUS DOI:10.7164/ANTIBIOTICS.38.767

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000421 Pseudomonas fluorescens
NCBITaxon:294
CLUSTER_UNSTATED genbank:AY061859.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000421MIBIG5

This page is generated from data/natural_products/alkaloids/safracin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.