saxitoxin
CHEBI:34970 EXACT SEEDED
An alkaloid isolated from the marine dinoflagellates and cyanobacteria that causes paralytic shellfish poisoning.
Structure
| Standard InChIKey | RPQXVSUAYFXFJA-HGRQIUPRSA-N |
|---|---|
| SMILES | C1CN2C(=N[C@H]([C@H]3[C@]2(C1(O)O)N=C(N3)N)COC(=O)N)N |
| Stereochemistry | fully defined |
| Cross-references | pubchem:37165, chembl:CHEMBL501134 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Cylindrospermopsis raciborskii T3 NCBITaxon:398006 |
SOURCE_ASSERTION | mibig:BGC0000188 | PMID:18487408 |
Occurrences 25
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Saxidomus nuttalli NCBITaxon:1129274 |
LOTUS | DOI:10.1016/0041-0101(85)90159-X |
| Saxidomus nuttalli NCBITaxon:1129274 |
LOTUS | DOI:10.1016/0198-0254(85)94069-5 |
| Anabaena NCBITaxon:1163 |
LOTUS | DOI:10.1016/0041-0101(86)90120-0 |
| Anabaena NCBITaxon:1163 |
LOTUS | DOI:10.1021/JA00838A045 |
| Aphanizomenon NCBITaxon:1175 |
LOTUS | DOI:10.1021/JA00838A045 |
| Aphanizomenon flos-aquae NCBITaxon:1176 |
LOTUS | DOI:10.1016/0041-0101(86)90120-0 |
| Aphanizomenon flos-aquae NCBITaxon:1176 |
LOTUS | DOI:10.1016/S0040-4039(00)80500-6 |
| Lingulodinium polyedra NCBITaxon:160621 |
LOTUS | DOI:10.1016/0041-0101(90)90150-6 |
| Takifugu radiatus NCBITaxon:176186 |
LOTUS | DOI:10.1016/0041-0101(84)90082-5 |
| Takifugu poecilonotus NCBITaxon:176188 |
LOTUS | DOI:10.1016/0041-0101(84)90082-5 |
| Takifugu vermicularis NCBITaxon:177060 |
LOTUS | DOI:10.1016/0041-0101(84)90082-5 |
| Gonyaulax NCBITaxon:2912 |
LOTUS | DOI:10.1351/PAC198254101973 |
| Gonyaulax catenella NCBITaxon:2925 |
LOTUS | DOI:10.1016/0041-0101(85)90031-5 |
| Gonyaulax catenella NCBITaxon:2925 |
LOTUS | DOI:10.1016/0041-0101(90)90132-Q |
| Gonyaulax catenella NCBITaxon:2925 |
LOTUS | DOI:10.1021/BI00868A011 |
| Gonyaulax tamarensis NCBITaxon:2926 |
LOTUS | DOI:10.1016/0041-0101(90)90132-Q |
| Gonyaulax tamarensis NCBITaxon:2926 |
LOTUS | DOI:10.1248/JHS1956.30.5_328 |
| Saxidomus gigantea NCBITaxon:410349 |
LOTUS | DOI:10.1021/JF60198A016 |
| Planktothrix NCBITaxon:54304 |
LOTUS | DOI:10.1016/0041-0101(86)90120-0 |
| Planktothrix NCBITaxon:54304 |
LOTUS | DOI:10.1021/JA00838A045 |
| Carcinoscorpius rotundicauda NCBITaxon:6848 |
LOTUS | DOI:10.1016/0041-0101(88)90064-5 |
| Carcinoscorpius rotundicauda NCBITaxon:6848 |
LOTUS | DOI:10.2331/SUISAN.53.261 |
| Pyrodinium bahamense NCBITaxon:73915 |
LOTUS | DOI:10.1016/0041-0101(84)90082-5 |
| Cylindrospermopsis NCBITaxon:77021 |
LOTUS | DOI:10.1016/0041-0101(86)90120-0 |
| Cylindrospermopsis NCBITaxon:77021 |
LOTUS | DOI:10.1021/JA00838A045 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000188 | Cylindrospermopsis raciborskii T3 NCBITaxon:398006 |
CLUSTER_UNSTATED | genbank:DQ787200.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000188 | MIBIG | 5 |
| CHEBI:34970 | CHEBI | 3-star |
This page is generated from data/natural_products/alkaloids/saxitoxin.yaml, which is generated from the committed inventories. Neither is edited by hand.