spiroindimicin B
naturalproductmech:mibig-a127194140 MINTED SEEDED
Structure
| Standard InChIKey | FEZAUMRIJDPBGI-HSZRJFAPSA-N |
|---|---|
| SMILES | COC(=O)C1=C2C(=CN1)C1=C(NC3=CC=C(Cl)C=C13)[C@@]21CN(C)C2=CC=C(Cl)C=C12 |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA018295 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces sp. SCSIO 03032 NCBITaxon:2878388 |
SOURCE_ASSERTION | mibig:BGC0001782 | PMID:28620687 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1007/S12539-013-0200-Y |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/OL301343N |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1038/SREP42382 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001782 | Streptomyces sp. SCSIO 03032 NCBITaxon:2878388 |
CLUSTER_UNSTATED | genbank:KY750719.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001782 | MIBIG | 3 |
This page is generated from data/natural_products/alkaloids/spiroindimicin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.