thienodolin
CHEBI:9543 EXACT SEEDED
An indole alkaloid that is a thienoindole ring with carboxamide group and chlorine substituents at positions 2 and 6 respectively.
Structure
| Standard InChIKey | LREDECYEGMWOAR-UHFFFAOYSA-N |
|---|---|
| SMILES | NC(=O)C1=CC2=C(NC3=C2C=CC(Cl)=C3)S1 |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA017595, pubchem:442119 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces albogriseolus NCBITaxon:1887 |
SOURCE_ASSERTION | mibig:BGC0001374 | PMID:24692213 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces alboflavus NCBITaxon:67267 |
LOTUS | DOI:10.1271/BBB.57.632 |
| Streptomyces albogriseolus NCBITaxon:1887 |
LOTUS | DOI:10.1002/CBIC.201600304 |
| Streptomyces albogriseolus NCBITaxon:1887 |
LOTUS | DOI:10.1271/BBB.57.632 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001374 | Streptomyces albogriseolus NCBITaxon:1887 |
CLUSTER_UNSTATED | genbank:KU569241.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001374 | MIBIG | 5 |
| CHEBI:9543 | CHEBI | 3-star |
This page is generated from data/natural_products/alkaloids/thienodolin.yaml, which is generated from the committed inventories. Neither is edited by hand.