TMC-169
naturalproductmech:mibig-e2d6335a11 MINTED SEEDED
Structure
| Standard InChIKey | PBMWGTZJDVBFGK-XSPGZUFDSA-N |
|---|---|
| SMILES | C[C@H]1[C@H]2[C@@H](NC(=O)[C@@]23[C@@H](/C=C(\CCCC(/C=C\C3=O)O)/C)C=C1C)CC(C)C |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA003204 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Aspergillus flavipes NCBITaxon:41900 |
BGC_CHARACTERIZED | mibig:BGC0002204 | PMID:32913332 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Aspergillus flavipes NCBITaxon:41900 |
LOTUS | DOI:10.7164/ANTIBIOTICS.52.575 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002204 | Aspergillus flavipes NCBITaxon:41900 |
CLUSTER_DEMONSTRATED | genbank:MT586757.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002204 | MIBIG | 3 |
This page is generated from data/natural_products/alkaloids/tmc-169.yaml, which is generated from the committed inventories. Neither is edited by hand.