NaturalProductMech

tolypyridone C

naturalproductmech:mibig-6749897cf4 MINTED SEEDED

Structure

Standard InChIKeyHLYMRXUSGGFLEA-CTXXGXLOSA-N
SMILESC/C=C/C[C@H](C)C[C@H](C)C(=O)C1=C(O)C(C2=CC=C(O)C=C2)=CNC1=O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA029476, pubchem:156580946

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Tolypocladium sp. 49Y
NCBITaxon:2789198
SOURCE_ASSERTION mibig:BGC0002230 DOI:10.1021/acs.jnatprod.0c00675

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Tolypocladium
NCBITaxon:29909
LOTUS DOI:10.1021/ACS.JNATPROD.0C00675

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002230 Tolypocladium sp. 49Y
NCBITaxon:2789198
CLUSTER_DEMONSTRATED genbank:MT127616.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002230MIBIG2

This page is generated from data/natural_products/alkaloids/tolypyridone-c.yaml, which is generated from the committed inventories. Neither is edited by hand.