welwitindolinone A isonitrile
naturalproductmech:mibig-fcc59363e7 MINTED SEEDED
Structure
| Standard InChIKey | XLRFBPJWPHKLJV-OKKVMHGVSA-N |
|---|---|
| SMILES | CC1(C)[C@H]2C[C@@H](Cl)[C@@](C)(C=C)C([N+]#[C-])=C2[C@]11C(=O)NC2=CC=CC=C12 |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA014803, cyanometdb:CyanoMetDB_1563 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Hapalosiphon welwitschii UTEX B 1830 NCBITaxon:1433842 |
SOURCE_ASSERTION | mibig:BGC0000668 | DOI:10.1021/jo00226a009 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Hapalosiphon welwitschii NCBITaxon:162986 |
LOTUS | DOI:10.1021/JA00101A015 |
| Hapalosiphon welwitschii NCBITaxon:162986 |
LOTUS | DOI:10.1021/JO00226A009 |
| Hapalosiphon welwitschii NCBITaxon:162986 |
CYANOMETDB | DOI:10.1021/ja00101a015 |
| Fischerella muscicola NCBITaxon:92938 |
LOTUS | DOI:10.1021/NP980485T |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000668 | Hapalosiphon welwitschii UTEX B 1830 NCBITaxon:1433842 |
CLUSTER_DEMONSTRATED | genbank:KF811479.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000668 | MIBIG | 5 |
This page is generated from data/natural_products/alkaloids/welwitindolinone-a-isonitrile.yaml, which is generated from the committed inventories. Neither is edited by hand.