xiamycin A
naturalproductmech:mibig-9f978c0043 MINTED SEEDED
Structure
| Standard InChIKey | XUTJPVCJXVRRLB-SKWRMQMOSA-N |
|---|---|
| SMILES | [H][C@@]12CCC3=C(C=C4C(NC5=C4C=CC=C5)=C3)[C@@]1(C)CC[C@H](O)[C@@]2(C)C(O)=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA012008, pubchem:38358410 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, other, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces sp. HKI0576 NCBITaxon:995841 |
BGC_CHARACTERIZED | mibig:BGC0000665 | DOI:10.1016/j.bmcl.2010.09.010 |
| Streptomyces sp. SCSIO 02999 NCBITaxon:1194094 |
BGC_CHARACTERIZED | mibig:BGC0000666 | PMID:22591327 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces xinghaiensis NCBITaxon:1038928 |
LOTUS | DOI:10.1007/S00253-018-9337-2 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1016/J.BMCL.2010.09.010 |
| Streptomyces olivaceus NCBITaxon:47716 |
LOTUS | DOI:10.3390/MD17100593 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000665 | Streptomyces sp. HKI0576 NCBITaxon:995841 |
CLUSTER_DEMONSTRATED | genbank:HE815466.1 |
| mibig:BGC0000666 | Streptomyces sp. SCSIO 02999 NCBITaxon:1194094 |
CLUSTER_DEMONSTRATED | genbank:JQ812811.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0000665, BGC0000666. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000665 | MIBIG | 5 |
| BGC0000666 | MIBIG | 5 |
This page is generated from data/natural_products/alkaloids/xiamycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.