2-hydroxymethylclavam
naturalproductmech:mibig-be860177f5 MINTED SEEDED
Structure
| Standard InChIKey | CRVXTEJTLQIKDI-XINAWCOVSA-N |
|---|---|
| SMILES | C1[C@H]2N(C1=O)C[C@@H](O2)CO |
| Stereochemistry | fully defined |
| Cross-references | pubchem:3050259 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces clavuligerus ATCC 27064 NCBITaxon:1901 |
BGC_CHARACTERIZED | mibig:BGC0000841 | PMID:10681345 |
| Streptomyces clavuligerus ATCC 27064 NCBITaxon:1901 |
BGC_CHARACTERIZED | mibig:BGC0000843 | PMID:22435762 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces clavuligerus NCBITaxon:1901 |
LOTUS | DOI:10.1128/AAC.01090-12 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000841 | Streptomyces clavuligerus ATCC 27064 NCBITaxon:1901 |
CLUSTER_DEMONSTRATED | genbank:CM000914.1 |
| mibig:BGC0000843 | Streptomyces clavuligerus ATCC 27064 NCBITaxon:1901 |
CLUSTER_DEMONSTRATED | genbank:CM000913.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0000841, BGC0000843. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000841 | MIBIG | 5 |
| BGC0000843 | MIBIG | 5 |
This page is generated from data/natural_products/amino_acids_and_peptides/2-hydroxymethylclavam.yaml, which is generated from the committed inventories. Neither is edited by hand.