NaturalProductMech

aerobactin

CHEBI:18157 EXACT SEEDED

Structure

Standard InChIKeyKDHHWXGBNUCREU-HOTGVXAUSA-N
SMILESCC(=O)N(CCCC[C@@H](C(=O)O)NC(=O)CC(CC(=O)N[C@@H](CCCCN(C(=O)C)O)C(=O)O)(C(=O)O)O)O
Stereochemistryfully defined
Cross-referencespubchem:123762

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 3

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Grimontia hollisae
NCBITaxon:673
SOURCE_ASSERTION mibig:BGC0000939 PMID:16809025
Xenorhabdus szentirmaii DSM 16338
NCBITaxon:1427518
SOURCE_ASSERTION mibig:BGC0001498 PMID:28654175
Pantoea ananatis
NCBITaxon:553
SOURCE_ASSERTION mibig:BGC0001499 PMID:30027301

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces wadayamensis
NCBITaxon:141454
LOTUS DOI:10.1128/GENOMEA.00625-14
Streptomyces nodosus
NCBITaxon:40318
LOTUS DOI:10.1007/S00253-015-7060-9
Escherichia coli
NCBITaxon:562
LOTUS DOI:10.1038/MSB.2011.65
Escherichia coli
NCBITaxon:562
CHEBI PMID:21988831
Pantoea ananatis
NCBITaxon:553
LOTUS DOI:10.1007/S00438-018-1477-7

Biosynthetic gene clusters 3

AccessionHostLocus evidenceGenome
mibig:BGC0000939 Grimontia hollisae
NCBITaxon:673
CLUSTER_UNSTATED genbank:AB199785.1
mibig:BGC0001498 Xenorhabdus szentirmaii DSM 16338
NCBITaxon:1427518
CLUSTER_UNSTATED genbank:CBXF010000089.1
mibig:BGC0001499 Pantoea ananatis
NCBITaxon:553
CLUSTER_UNSTATED genbank:MH015021.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000939, BGC0001498, BGC0001499. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0000939MIBIG5
BGC0001498MIBIG5
BGC0001499MIBIG5
CHEBI:18157CHEBI3-star

This page is generated from data/natural_products/amino_acids_and_peptides/aerobactin.yaml, which is generated from the committed inventories. Neither is edited by hand.