NaturalProductMech

alanylclavam

naturalproductmech:mibig-23fd94d01a MINTED SEEDED

Structure

Standard InChIKeyKCAIYJDHLVYANU-VPLCAKHXSA-N
SMILESC1[C@H]2N(C1=O)C[C@@H](O2)C[C@@H](C(=O)O)N
Stereochemistryfully defined
Cross-referencespubchem:194618

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces clavuligerus ATCC 27064
NCBITaxon:1901
BGC_CHARACTERIZED mibig:BGC0000841 PMID:10681345
Streptomyces clavuligerus ATCC 27064
NCBITaxon:1901
BGC_CHARACTERIZED mibig:BGC0000843 PMID:22435762

Occurrences 7

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces clavuligerus
NCBITaxon:1901
LOTUS DOI:10.1002/ECE3.4924
Streptomyces clavuligerus
NCBITaxon:1901
LOTUS DOI:10.1016/S0378-1119(98)00106-1
Streptomyces clavuligerus
NCBITaxon:1901
LOTUS DOI:10.1128/AAC.01090-12
Streptomyces clavuligerus
NCBITaxon:1901
LOTUS DOI:10.1128/AAC.44.3.720-726.2000
Streptomyces clavuligerus
NCBITaxon:1901
LOTUS DOI:10.1139/W2012-012
Streptomyces clavuligerus
NCBITaxon:1901
LOTUS DOI:10.7164/ANTIBIOTICS.36.208
Streptomyces clavuligerus
NCBITaxon:1901
LOTUS DOI:10.7164/ANTIBIOTICS.36.217

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0000841 Streptomyces clavuligerus ATCC 27064
NCBITaxon:1901
CLUSTER_DEMONSTRATED genbank:CM000914.1
mibig:BGC0000843 Streptomyces clavuligerus ATCC 27064
NCBITaxon:1901
CLUSTER_DEMONSTRATED genbank:CM000913.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000841, BGC0000843. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0000841MIBIG5
BGC0000843MIBIG5

This page is generated from data/natural_products/amino_acids_and_peptides/alanylclavam.yaml, which is generated from the committed inventories. Neither is edited by hand.