avoparcin
naturalproductmech:mibig-255dcd6740 MINTED SEEDED antibacterial
Structure
| Standard InChIKey | OTKPPUXRIADSGD-PPRNARJGSA-N |
|---|---|
| SMILES | C[C@H]1[C@@H]([C@@H](C[C@@H](O1)O[C@H]2[C@H]3C(=O)N[C@@H](C4=CC(=CC(=C4C5=C(C=CC(=C5)[C@H](C(=O)N3)NC(=O)[C@H]6C7=CC(=C(C(=C7)OC8=C(C=C2C=C8)Cl)O[C@H]9C([C@H]([C@@H]([C@H](O9)CO)O)O)O[C@H]1C[C@H]([C@H]([C@@H](O1)C)O)N)OC1=CC=C(C=C1)[C@H]([C@H](C(=O)N[C@H](C(=O)N6)C1=CC=C(C=C1)O)NC(=O)[C@@H](C1=CC=C(C=C1)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O)O)NC)O)O)O)O)C(=O)O)N)O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:16132294 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Amycolatopsis coloradensis NCBITaxon:76021 |
SOURCE_ASSERTION | mibig:BGC0001462 | DOI:10.1099/00207713-45-1-124 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Amycolatopsis coloradensis NCBITaxon:76021 |
LOTUS | DOI:10.1099/00207713-45-1-124 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001462 | Amycolatopsis coloradensis NCBITaxon:76021 |
CLUSTER_UNSTATED | genbank:MQUQ01000006.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — antibioticmech:aro-9aee56c696 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001462 | MIBIG | 5 |
This page is generated from data/natural_products/amino_acids_and_peptides/avoparcin.yaml, which is generated from the committed inventories. Neither is edited by hand.