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bacilysin

naturalproductmech:mibig-080d9481a3 MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.
What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKeyJJOSOKMLZZVGKD-INVWQFOESA-N
SMILESC[C@@H](C(=O)OC(=O)[C@H](CC1CCC(=O)[C@H]2[C@@H]1O2)N)N
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:160175

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Bacillus velezensis FZB42
NCBITaxon:326423
BGC_CHARACTERIZED mibig:BGC0001184 PMID:19061923

Occurrences 6

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Bacillus subtilis
NCBITaxon:1423
LOTUS DOI:10.1007/BF02884030
Bacillus subtilis
NCBITaxon:1423
LOTUS DOI:10.1042/BJ1180563
Bacillus subtilis
NCBITaxon:1423
LOTUS DOI:10.1128/JB.170.1.482-484.1988
Bacillus subtilis
NCBITaxon:1423
LOTUS DOI:10.7164/ANTIBIOTICS.39.888
Bacillus subtilis
NCBITaxon:1423
LOTUS DOI:10.7164/ANTIBIOTICS.40.1677
Bacillus velezensis
NCBITaxon:492670
LOTUS DOI:10.1016/J.JBIOTEC.2008.10.015

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001184 Bacillus velezensis FZB42
NCBITaxon:326423
CLUSTER_DEMONSTRATED genbank:CP000560.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

PRODUCERS & OCCURRENCE 1 producer (1 causal) 6 cited occurrences BIOSYNTHETIC LOCUS 1 gene cluster 0 curated pathway steps NATURAL PRODUCT bacilysin naturalproductmech:mibig-080d9481a3 Amino acids and peptides TARGETS & BIOACTIVITY 0 molecular targets 0 bioactivities · 0 graphs

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Provenance

Source conceptSourceVersion
BGC0001184MIBIG4

This page is generated from data/natural_products/amino_acids_and_peptides/bacilysin.yaml, which is generated from the committed inventories. Neither is edited by hand.