NaturalProductMech

benzylpenicillin sodium

CHEBI:51765 EXACT SEEDED

Structure

Standard InChIKeyFCPVYOBCFFNJFS-LQDWTQKMSA-M
SMILESCC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[Na+]
Stereochemistryfully defined
Cross-referencespubchem:23668834

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Penicillium chrysogenum
NCBITaxon:5076
SOURCE_ASSERTION mibig:BGC0000404 DOI:10.1016/s0140-6736(00)87452-8
Penicillium chrysogenum
NCBITaxon:5076
SOURCE_ASSERTION mibig:BGC0000405 PMID:1368505

Occurrences 0

None cited.

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0000404 Penicillium chrysogenum
NCBITaxon:5076
CLUSTER_UNSTATED genbank:DQ192518.1
mibig:BGC0000405 Penicillium chrysogenum
NCBITaxon:5076
CLUSTER_DEMONSTRATED genbank:EF601124.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 2

name-disagreement — ChEBI calls this structure 'benzylpenicillin sodium' and MIBiG calls it 'penicillin'. They share a Standard InChIKey, so if the names denote different compounds then one upstream record has the wrong structure. Check which.

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000404, BGC0000405. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0000404MIBIG4
BGC0000405MIBIG5
CHEBI:51765CHEBI3-star

This page is generated from data/natural_products/amino_acids_and_peptides/benzylpenicillin-sodium.yaml, which is generated from the committed inventories. Neither is edited by hand.