NaturalProductMech

carbapenem MM4550

naturalproductmech:mibig-5bc03ef6c3 MINTED SEEDED

Structure

Standard InChIKeyRIBHTDFMGKDYOQ-ONEGZZNKSA-N
SMILESO=C1C(C(C)OS(=O)(O)=O)C2N1C(C(O)=O)C(S(/C=C/NC(C)=O)=O)C2
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces argenteolus
NCBITaxon:67274
BGC_CHARACTERIZED mibig:BGC0000842 PMID:24420617

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces griseus
NCBITaxon:1911
LOTUS DOI:10.1002/CBIC.201300319
Streptomyces argenteolus
NCBITaxon:67274
LOTUS DOI:10.1002/CBIC.201300319

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000842 Streptomyces argenteolus
NCBITaxon:67274
CLUSTER_DEMONSTRATED genbank:KF042303.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000842MIBIG5

This page is generated from data/natural_products/amino_acids_and_peptides/carbapenem-mm4550.yaml, which is generated from the committed inventories. Neither is edited by hand.