NaturalProductMech

chloroeremomycin

CHEBI:29556 EXACT SEEDED antibacterial

A complex glycopeptide antibiotic that is isolated from Amycolatopsis orientalis.

Structure

Standard InChIKeyXJHXLMVKYIVZTE-LOALFDMRSA-N
SMILESC[C@H]1[C@@H]([C@@](C[C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O[C@H]1C[C@]([C@H]([C@@H](O1)C)O)(C)N)NC7=O)C(=O)O)O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)(C)N)O
Stereochemistryfully defined
Cross-referencespubchem:445806

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Amycolatopsis orientalis
NCBITaxon:31958
SOURCE_ASSERTION mibig:BGC0000322 PMID:9545426

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Amycolatopsis orientalis
NCBITaxon:31958
CHEBI Naoki,J.Antibiotics,41,(1988),1506

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000322 Amycolatopsis orientalis
NCBITaxon:31958
CLUSTER_UNSTATED genbank:AJ223999.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Elsewhere in the fleet

Provenance

Source conceptSourceVersion
BGC0000322MIBIG3
CHEBI:29556CHEBI3-star

This page is generated from data/natural_products/amino_acids_and_peptides/chloroeremomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.