NaturalProductMech

chrysobactin

CHEBI:61345 EXACT SEEDED

A catechol-type siderophore with a structure of D-lysyl-L-serine substituted on N2 of the lysyl residue by a 2,3-dihydroxybenzoyl group. It is produced by the Gram-negative bacillus Dickeya dadantii (previously known as Erwinia chrysanthem). Only the catecholate hydroxyl groups participate in metal coordination, so chrysobactin cannot provide full 1:1 coordination of Fe(III); at neutral pH and concentrations of about 0.1 mM, ferric chrysobactin exists as a mixture of bis and tris complexes.

Structure

Standard InChIKeyNNTXFOAPABMVEG-MNOVXSKESA-N
SMILESC1=CC(=C(C(=C1)O)O)C(=O)N[C@H](CCCCN)C(=O)N[C@@H](CO)C(=O)O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA009561

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Dickeya chrysanthemi
NCBITaxon:556
SOURCE_ASSERTION mibig:BGC0002414 PMID:34603680

Occurrences 6

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Pseudomonas luteola
NCBITaxon:47886
LOTUS DOI:10.1515/ZNC-1996-5-603
Dickeya chrysanthemi
NCBITaxon:556
LOTUS DOI:10.1016/S0021-9258(18)94049-4
Dickeya chrysanthemi
NCBITaxon:556
LOTUS DOI:10.1021/IC801143E
Dickeya chrysanthemi
NCBITaxon:556
LOTUS DOI:10.1021/NP200126Z
Dickeya chrysanthemi
NCBITaxon:556
LOTUS DOI:10.1104/PP.102.3.967
Dickeya chrysanthemi
NCBITaxon:556
CHEBI PMID:18803373

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002414 Dickeya chrysanthemi
NCBITaxon:556
CLUSTER_UNSTATED genbank:JAFCAF010000006.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002414MIBIG3
CHEBI:61345CHEBI3-star

This page is generated from data/natural_products/amino_acids_and_peptides/chrysobactin.yaml, which is generated from the committed inventories. Neither is edited by hand.