colistin A
CHEBI:59064 EXACT SEEDED antibacterial
A polymyxin having a (6R)-6-methyloctanoyl group at the amino terminus.
Structure
| Standard InChIKey | XDJYMJULXQKGMM-RVYUQJQSSA-N |
|---|---|
| SMILES | CC[C@@H](C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC1=O)CCN)CC(C)C)CC(C)C)CCN)CCN)[C@@H](C)O |
| Stereochemistry | fully defined |
| Cross-references | pubchem:202195 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Paenibacillus alvei NCBITaxon:44250 |
SOURCE_ASSERTION | mibig:BGC0001192 | PMID:25609230 |
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001192 | Paenibacillus alvei NCBITaxon:44250 |
CLUSTER_UNSTATED | genbank:KP262070.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:59064 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001192 | MIBIG | 5 |
| CHEBI:59064 | CHEBI | 3-star |
This page is generated from data/natural_products/amino_acids_and_peptides/colistin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.