cycloserine
naturalproductmech:mibig-415a4f90e6 REVIEW_NEEDED SEEDED antimycobacterial
Structure
| Standard InChIKey | DYDCUQKUCUHJBH-UWTATZPHSA-N |
|---|---|
| SMILES | N[C@@H]1CONC1=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA01237 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces lavendulae subsp. lavendulae NCBITaxon:58340 |
SOURCE_ASSERTION | mibig:BGC0000896 | PMID:20086163 |
Occurrences 7
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces lavendulae NCBITaxon:1914 |
LOTUS | DOI:10.1007/S00253-014-5988-9 |
| Streptomyces lavendulae NCBITaxon:1914 |
LOTUS | DOI:10.1016/J.GENE.2008.07.043 |
| Streptomyces lavendulae NCBITaxon:1914 |
LOTUS | DOI:10.1016/J.JBIOSC.2015.08.013 |
| Streptomyces lavendulae NCBITaxon:1914 |
LOTUS | DOI:10.1074/JBC.M404603200 |
| Streptomyces lavendulae NCBITaxon:1914 |
LOTUS | DOI:10.1074/JBC.M611319200 |
| Streptomyces lavendulae NCBITaxon:1914 |
LOTUS | DOI:10.1128/AAC.01226-09 |
| Streptomyces garyphalus NCBITaxon:235466 |
LOTUS | DOI:10.1007/BF01053994 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000896 | Streptomyces lavendulae subsp. lavendulae NCBITaxon:58340 |
CLUSTER_UNSTATED | genbank:AB516431.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:40009 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000896 | MIBIG | 5 |
| CHEBI:40009 | CHEBI | 3-star |
| CHEBI:74159 | CHEBI | 3-star |
This page is generated from data/natural_products/amino_acids_and_peptides/cycloserine.yaml, which is generated from the committed inventories. Neither is edited by hand.