cyclosporin C
naturalproductmech:mibig-a915d3af4f MINTED SEEDED
Structure
| Standard InChIKey | JTOKYIBTLUQVQV-QRVTZXGZSA-N |
|---|---|
| SMILES | C/C=C/C[C@@H](C)[C@H]([C@H]1C(=O)N[C@H](C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)[C@@H](C)O)O |
| Stereochemistry | fully defined |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Beauveria felina NCBITaxon:37994 |
SOURCE_ASSERTION | mibig:BGC0001565 | DOI:10.1007/s00253-018-8792-0 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Fusarium neocosmosporiellum NCBITaxon:1325723 |
LOTUS | DOI:10.1271/BBB1961.53.2291 |
| Trichoderma polysporum NCBITaxon:40695 |
LOTUS | DOI:10.1002/CHIN.198720311 |
| Trichoderma polysporum NCBITaxon:40695 |
LOTUS | DOI:10.1002/HLCA.19770600414 |
| Gliomastix luzulae NCBITaxon:61182 |
LOTUS | DOI:10.1128/AEM.63.5.1739-1743.1997 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001565 | Beauveria felina NCBITaxon:37994 |
CLUSTER_UNSTATED | genbank:MF716954.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001565 | MIBIG | 4 |
This page is generated from data/natural_products/amino_acids_and_peptides/cyclosporin-c.yaml, which is generated from the committed inventories. Neither is edited by hand.