cyclothiazomycin b1
naturalproductmech:mibig-0bd0a2e60f MINTED SEEDED
Structure
| Standard InChIKey | GMFKDKZZMAPRGJ-GLERVACHSA-N |
|---|---|
| SMILES | [H][C@]12CSC(=N1)C1=CSC(=N1)C1=CSC(=N1)C(=C)NC(=O)[C@@]1([H])CSC(=N1)C1=CSC(=N1)C1=CC=C3C(=N1)[C@H](C)NC(=O)[C@]1([H])CCCN1C(=O)\C(NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)C(C)(NC(=O)\C(NC(=O)C1CSC(=N1)[C@H](CC(N)=O)NC3=O)=C\C)SC[C@H](NC2=O)C(O)=O)=C\C |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA09917 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces mobaraensis NBRC 13819 = DSM 40847 NCBITaxon:1223523 |
SOURCE_ASSERTION | mibig:BGC0001145 | PMID:24937678 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1016/J.BMC.2006.09.006 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001145 | Streptomyces mobaraensis NBRC 13819 = DSM 40847 NCBITaxon:1223523 |
CLUSTER_UNSTATED | genbank:AORZ01000028.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001145 | MIBIG | 5 |
This page is generated from data/natural_products/amino_acids_and_peptides/cyclothiazomycin-b1.yaml, which is generated from the committed inventories. Neither is edited by hand.