cyclothiazomycin
naturalproductmech:mibig-433e947767 MINTED SEEDED
Structure
| Standard InChIKey | OGUUCNCVZHZWGA-SKEOMMRSSA-N |
|---|---|
| SMILES | [H][C@](C)(O)[C@]1([H])NC(=O)[C@@]2(C)NC(=O)\C(NC(=O)[C@]3([H])CSC(=N3)[C@]([H])(CC(N)=O)NC(=O)C3=CC=C(N=C3[C@@]([H])(C)NC(=O)[C@]3([H])CCCN3C(=O)\C(NC(=O)CNC1=O)=C\C)C1=NC(=CS1)C1=N[C@@]([H])(CS1)C(=O)NC(=C)C1=NC(=CS1)C1=NC(=CS1)C1=N[C@@]([H])(CS1)C(=O)N[C@@]([H])(CS2)C(O)=O)=C\C |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA02427 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is ribosomal, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces hygroscopicus NCBITaxon:1912 |
SOURCE_ASSERTION | mibig:BGC0000603 | PMID:24937678 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1016/0040-4039(91)80859-5 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000603 | Streptomyces hygroscopicus NCBITaxon:1912 |
CLUSTER_DEMONSTRATED | genbank:FJ472825.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000603 | MIBIG | 5 |
This page is generated from data/natural_products/amino_acids_and_peptides/cyclothiazomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.