NaturalProductMech

decaplanin

naturalproductmech:mibig-de067fa3d6 MINTED SEEDED

Structure

Standard InChIKeySJSZMXQSCZCGFO-UHFFFAOYSA-N
SMILESCC1C(C(C(C(O1)OC2C(C(C(OC2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)C(C(C(=O)NC(C(=O)NC5C(=O)NC7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9C(NC(=O)C(C(C1=CC=C(O4)C=C1)OC1CC(C(C(O1)C)O)(C)N)NC7=O)C(=O)O)O)O)CC(=O)N)NC(=O)C(CC(C)C)NC)O)Cl)CO)O)O)O)O)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:195570

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Amycolatopsis regifaucium
NCBITaxon:546365
SOURCE_ASSERTION mibig:BGC0001459 PMID:17978218
Amycolatopsis decaplanina DSM 44594
NCBITaxon:1284240
SOURCE_ASSERTION mibig:BGC0001460 PMID:14742486

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Amycolatopsis decaplanina
NCBITaxon:208441
LOTUS DOI:10.1099/IJS.0.02586-0
Amycolatopsis regifaucium
NCBITaxon:546365
LOTUS DOI:10.1099/IJS.0.64974-0

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0001459 Amycolatopsis regifaucium
NCBITaxon:546365
CLUSTER_UNSTATED genbank:LOBU02000007.1
mibig:BGC0001460 Amycolatopsis decaplanina DSM 44594
NCBITaxon:1284240
CLUSTER_UNSTATED genbank:AOHO01000074.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0001459, BGC0001460. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0001459MIBIG5
BGC0001460MIBIG5

This page is generated from data/natural_products/amino_acids_and_peptides/decaplanin.yaml, which is generated from the committed inventories. Neither is edited by hand.