NaturalProductMech

EDHA

naturalproductmech:mibig-1d6d8308ed MINTED SEEDED

Structure

Standard InChIKeyUULSZYUKAFTXQP-UHFFFAOYSA-N
SMILESOC(CC(C(O)=O)NCCNC(C(O)=O)CC(O)CNC(N)=N)=O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:124628

Filing pathway

Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 3

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. MA5143a
NCBITaxon:2083010
BGC_CORRELATED mibig:BGC0002567 DOI:10.1039/c8mt00009c
Streptomyces avermitilis MA-4680 = NBRC 14893
NCBITaxon:227882
SOURCE_ASSERTION mibig:BGC0001587 PMID:29667664
Streptomyces scabiei 87.22
NCBITaxon:680198
SOURCE_ASSERTION mibig:BGC0002568 DOI:10.1039/c8mt00009c

Occurrences 0

None cited.

Biosynthetic gene clusters 3

AccessionHostLocus evidenceGenome
mibig:BGC0002567 Streptomyces sp. MA5143a
NCBITaxon:2083010
CLUSTER_CORRELATED genbank:OLMK01000008.1
mibig:BGC0001587 Streptomyces avermitilis MA-4680 = NBRC 14893
NCBITaxon:227882
CLUSTER_UNSTATED genbank:BA000030.3
mibig:BGC0002568 Streptomyces scabiei 87.22
NCBITaxon:680198
CLUSTER_UNSTATED genbank:FN554889.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0001587, BGC0002567, BGC0002568. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0002567MIBIG2
BGC0001587MIBIG5
BGC0002568MIBIG2

This page is generated from data/natural_products/amino_acids_and_peptides/edha.yaml, which is generated from the committed inventories. Neither is edited by hand.