EDHA
naturalproductmech:mibig-1d6d8308ed MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | UULSZYUKAFTXQP-UHFFFAOYSA-N |
|---|---|
| SMILES | OC(CC(C(O)=O)NCCNC(C(O)=O)CC(O)CNC(N)=N)=O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:124628 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 3
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces sp. MA5143a NCBITaxon:2083010 |
BGC_CORRELATED | mibig:BGC0002567 | DOI:10.1039/c8mt00009c |
| Streptomyces avermitilis MA-4680 = NBRC 14893 NCBITaxon:227882 |
SOURCE_ASSERTION | mibig:BGC0001587 | PMID:29667664 |
| Streptomyces scabiei 87.22 NCBITaxon:680198 |
SOURCE_ASSERTION | mibig:BGC0002568 | DOI:10.1039/c8mt00009c |
Occurrences 0
None cited.
Biosynthetic gene clusters 3
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002567 | Streptomyces sp. MA5143a NCBITaxon:2083010 |
CLUSTER_CORRELATED | genbank:OLMK01000008.1 |
| mibig:BGC0001587 | Streptomyces avermitilis MA-4680 = NBRC 14893 NCBITaxon:227882 |
CLUSTER_UNSTATED | genbank:BA000030.3 |
| mibig:BGC0002568 | Streptomyces scabiei 87.22 NCBITaxon:680198 |
CLUSTER_UNSTATED | genbank:FN554889.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0001587, BGC0002567, BGC0002568. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002567 | MIBIG | 2 |
| BGC0001587 | MIBIG | 5 |
| BGC0002568 | MIBIG | 2 |
This page is generated from data/natural_products/amino_acids_and_peptides/edha.yaml, which is generated from the committed inventories. Neither is edited by hand.