β-ethynylserine
naturalproductmech:mibig-1ab8038bd1 REVIEW_NEEDED SEEDED antibacterial
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | RBWXRFBKVDBXEG-DMTCNVIQSA-N |
|---|---|
| SMILES | C#C[C@H]([C@@H](C(=O)O)N)O |
| Stereochemistry | fully defined |
| Cross-references | pubchem:127838 |
Filing pathway
Amino acids and peptides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces cattleya NRRL 8057 = DSM 46488 NCBITaxon:1003195 |
SOURCE_ASSERTION | mibig:BGC0001994 | PMID:30867596 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces cattleya NCBITaxon:29303 |
LOTUS | DOI:10.7164/ANTIBIOTICS.39.304 |
| Streptomyces cattleya NCBITaxon:29303 |
CHEBI | PMID:3082841 |
| Athelia rolfsii NCBITaxon:39291 |
LOTUS | DOI:10.1016/0031-9422(71)85083-5 |
| Sclerotium rolfsii NCBITaxon:39291 |
CHEBI | Potgieter, H.C., Vermeulen, N.M.J., Potgieter, D.J.J. and Strauss, H.F. (1977) A toxic amino acid, 2(S)3(R)-2-amino-3-hydroxypent-4-ynoic acid from the fungus Sclerotiua rolfsii. Phytochemistry, 16, 1757-1759. |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001994 | Streptomyces cattleya NRRL 8057 = DSM 46488 NCBITaxon:1003195 |
CLUSTER_DEMONSTRATED | genbank:NC_016113.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Elsewhere in the fleet
- AntibioticMech — CHEBI:144729 (same structure, same inchikey)
- AntibioticMech — CHEBI:144833 (same structure, same inchikey)
Explore across X-Mech
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001994 | MIBIG | 4 |
| CHEBI:144729 | CHEBI | 3-star |
| CHEBI:144833 | CHEBI | 3-star |
This page is generated from data/natural_products/amino_acids_and_peptides/ethynylserine.yaml, which is generated from the committed inventories. Neither is edited by hand.